Thorough Utilization of Traditional Medicinal Plants, Diah Dhianawaty Djunaedi Received Professorship of Biochemistry and Molecular Biology
[Unpad.ac.id, 29/12/2016] There are a variety of plants that can be used as traditional medicine for urinary tract stones, one of which is sow thistle. Sow thistle leaves are believed to provide two synergistic effects in the treatment process of bladder stone disease, which can suppress the development of heavy rock and shed existing stone.
It was delivered by Prof. Dr. Diah Dhianawaty Djunaedi, dra. M.Sc., during her scientific speech in regard of Revenue Positions in the Field of Science of Professor of Biochemistry and Molecular Biology at the Faculty of Medicine, Universitas Padjadjaran, in the Multipurpose Room Building 2, Floor 4, Thursday (29/12). The speech entitled “Study Ethnopharmacology Plants for Overcoming Bladder Stone”.
In her research, Prof. Diah evaluated the activity of anti bladder stones through in vitro assays and in vivo. In addition of sow thistle leaves, Prof. Diah also examined the effectiveness of the cat’s whiskers leaves and chamber bitter herbs. Of the three of these plants, it was leaves of sow thistle that have significant effect for treatment of urinary tract stones.
The study was conducted on oxalate stones in the bladder with a model of oxalate stones in the bladder induced strain of male Wistar rats made with glycolic acid matrix method. Anti rocks activity test was divided in two treatment attempts, namely the prevention and treatment efforts.
“Both the synergistic effect is a new thing that is revealed by this study, in addition to the diuretic ability that helps dissolve and remove through urination,” said Prof. Diah.
Furthermore, the study was intended to determine the active compounds contained in sow thistle through fractionation process. “From this research obtained by standard methods short and fast for the isolation and purification of luteolin and apigenin from sow thistle leaves,” she said.
In addition to proof of pharmacology, the study has also been through the support of medical biochemistry test. According to Prof. Diah, biochemistry test plays an important role in the field of modern medicine. Biochemistry test on traditional medicinal plants acted as safety parameters, including efficacy, of the test plants, both in preclinical and clinical trials.
To determine the safety utilization sow thistle leaves as anti-bladder stones, acute toxicity test of the preparation sow thistle leaf decoction. From the test results, we can conclude that the decoction or boiled water sow thistle leaves the relative safety of the liver and kidneys.
“The study of empirical data on the traditional herbal medicines for kidney stones and bladder stones has been demonstrated experimentally preclinical pharmacology and safety have been tested with the support of medical biochemistry test. This shows that particular Biochemical Sciences Medical Biochemistry is associated with human health and disease that can provide the foundation to support the diagnosis and the use of traditional medicine,” said Prof. Diah. *
Reported by Artanti Hendriyana/am