Rector of Unpad Inaugurated Five New Professors
[unpad.ac.id, 04/8/2018] Five new professors of Unpad read a scientific speech in order to inaugurating ceremony at Grha Sanusi Hardjadinata, Friday (3/8) and Saturday (4/8).
On the first day, a scientific speech was read by Prof. Dr. Reiza D. Dienaputra, M.Hum., from the Faculty of Cultural Sciences, and Prof. Dr. Ani Melani Maskoen, drg., M.Kes., and Prof. Dr. Inne Suherna Sasmita, drg., Sp.P. (K) from the Faculty of Dentistry.
On the second day, the scientific speech was read by Prof. Dr. Achmad Hussein S. Kartamihardja, dr., Sp. KN., M.H. Kes. and Prof. Dr. Oki Suwarsa, Dr., Sp.KK (K)., M.Kes. from the Faculty of Medicine.
In a scientific speech entitled “Historical Disruption”, Prof. Reiza explained that historical disruption was needed by History and historians as it provides some benefits.
Prof. Reiza said, the first major benefit of historical disruption is the growth of the ability of History to read and anticipate the development of the era.
The past for History is only limited to material for reconstructing history as events into history as stories. While the method and the source of reconstruction will always change and move dynamically along with the development of human civilization.
“With disruption, History will always be able to adjust to the needs of certain era. History, despite talking about the past but it becomes a science that connect to the present and the future,” explained the Professor of History.
The second one, is to provide space for historians to always strive to develop their competence and abilities in the midst of the development of information and communication technology that moves very dynamically.
In addition, Prof. Ani of the Faculty of Medicine read a speech entitled “The Role of Molecular Genetics in the Cleft Lip Pathogenesis”. In her speech, She revealed that the molecular genetics approach is expected to be the driving force behind the search for a solution to the etiology of the cleft lip and palate, so that can be found a way to reduce the birth of patients with cleft lip and palate.
“The clinical solution that is expected later from this research is to prevent the occurrence of this disorder as early as possible,” said Prof. Ani who was inaugurated in the Field of Oral Biology.
The exact cause of cleft lip and palate is still unknown and this condition cannot be prevented but most scientists believe that it caused by a combination of genetic and environmental factors.
Prof. Ani also suggested for those who have family members with cleft lip and palate to avoid exposure to environmental factors suspected to be the cause of the disorder, such as pesticides, use of corticosteroid drugs, smoking, and other factors.
Meanwhile, Prof. Inne read a scientific speech entitled “Prognosis of Oral Rhabdomyosarcoma Cancer Using P27kip1 and Its Coactivators as Predictors of Child Patient Survival”.
Prof. Inne explained that the Imuno expression of p27Kip1 and coactivator p45Skp2 and p38Jab1 can be used as predictors of oral rhabdomyolysis (RMS) in children based on the stage (stadium) so that the development of cancer can be prevented earlier.
“The low immuno-expression of p27Kip1 and the high immuno expression of co-activator p45Skp2 and p38Jab1 in RMS of the child’s mouth can cause changes in cell cycle regulation, increase in the progressiveness and aggressiveness of cancer cells,” said the professor in the Child Dentistry.
On the second day, Saturday (4/8) Professor of Unpad Nuclear Medicine, Prof. Achmad Hussein read a scientific speech entitled “The Role of Theranostics of Nuclear Medicine in the Personalized Medicine Paradigm and Targeted Therapy”.
He explained that the paradigm of disease treatment is always changing in accordance with the development of medical science and technology. Currently developing a personalized medicine paradigm that encourages other concepts in medicine known as theranostics. Theranostics terminology is formed from two main pillars in the field of medicine, namely therapy and diagnostics.
The interesting fact about the concept of theranostics is the approach in the selection of promising therapies based on the specific molecular image of a disease; greater ability to predict severe side effects; and is a new way to objectively monitor therapeutic responses.
Further Prof. Achmad Hussein said that theranostics nanoparticles have the potential to change the pattern of disease management. The ideal nanoparticles for theranostics must be able to accumulate quickly and selectively in the desired target, providing information on the biochemical and morphological characteristics of the disease; efficient in providing appropriate drug effects without damaging healthy organs; cleaning of the body can take several hours or break down into by-products that are non-toxic, and safe for humans.
“The tendency of using Theranostics nanoparticles to produce disease management based on personalized medicine concepts and targeted therapies need not be doubted and the benefits are very clear, but many challenges must be overcome. The challenges are in the best nanoplatform selection, increased ligand conjugation efficiency, the development of ideal and effective synthetic techniques, high reproducibility, and of course a more efficient cost,” He said.
Meanwhile, in a scientific speech entitled “Allergy Drug Eruption: Perspective of Science, Health, and Society”, Prof. Oki said that the incidence of allergic drug eruptions was quite high in Indonesia. Allergic drug eruptions can manifest various clinical features ranging from maculo-papular rash, urticaria/angioedema, AGEP, erythroderma, DRESS, to severe ones such as SJS/TEN.
“This situation can interfere quality of life of patients, even ending with death,” said the Professor of Dermatology-Venereology.
Investigations in the form of skin tests, patch tests until oral provocation tests can help to look for etiology. Cessation as soon as possible the drugs suspected to be the cause, comprehensive management, and good education for doctors and the community are expected to improve the quality of life and prevent death. *
Reported by Artanti Hendriyana/am | Translated by dfa