[Unpad Media Channel] Wahyu Safriansyah has successfully earned his Doctorate in Chemistry from the Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Padjadjaran, at the remarkably young age of 25 years and 10 months. He defended his dissertation titled “Terpenoids and Steroids from the Bark of Aglaia pachyphylla and Their Cytotoxic and Anti-Inflammatory Activities” during the Doctoral Promotion Session held at the Einstein Room, FMIPA Unpad, Jatinangor, on Wednesday, July 9,th 2025.
His supervisory committee included Prof. Dr. Desi Harneti Putri Huspa, M.Si. (Chair), Prof. Dr. Unang Supratman, MS., and Dr. Mohamad Nurul Azmi (USM Malaysia). The examining committee comprised Prof. Dr. Tati Herlina, M.Si., Dr. Shabarni Gaffar, M.Si., and Dr. Sofa Fajriah, M.Si. (BRIN).
“In short, I explored potential novel compounds from the terpenoid and steroid groups that may serve as anti-cancer or anti-inflammatory agents, particularly for breast cancer,” Wahyu explained during an interview with the Unpad Media Channel team on July 14th, 2025.
Wahyu completed his doctoral studies through the Pendidikan Magister menuju Doktor untuk Sarjana Unggul (PMDSU) scholarship program. He hopes his achievement will inspire and contribute to the improvement of human resource quality in Indonesia. His passion for research was one of the key motivations behind choosing this path.
Wahyu’s dedication to research is evident from his work in isolating 28 compounds from the bark of Aglaia pachyphylla, six of which were identified as novel terpenoid and steroid compounds. He has also published 17 scientific articles in reputable international journals. During his studies, Wahyu participated in a sandwich program at Universiti Pendidikan Sultan Idris (Malaysia) and Osaka University (Japan).
“Since Indonesia still lacks certain research instruments essential for my field, collaboration with various institutions is necessary. We need to exchange perspectives to enhance the quality of our research,” explained Wahyu.
Wahyu also expressed hope that Indonesia’s research infrastructure will continue to improve and become more evenly distributed. “My hope is that, in the future, Indonesia will have more advanced research facilities. This would allow researchers to conduct independent studies within the country and support the acceleration of national human resource development,” he added.
Below is the list of Wahyu Safriansyah’s published works:
- Phytochemistry and Biological Activities of Guarea Genus (Meliaceae)
- Sesquiterpenoids from the stem bark of Aglaia pachyphylla Miq (Meliaceae) and cytotoxic activity against MCF-7 Cancer Cell Line
- The isolation of novel pregnane steroids from Aglaia pachyphylla Miq. and the cytotoxicity against breast cancer cell lines (MCF-7)
- Pachyphyllanone, a new cycloartane triterpenoid isolated from Aglaia pachyphylla and its cytotoxic activity
- Secondary Metabolites of Biscogniauxia: Distribution, Chemical Diversity, Bioactivity, and Implications of the Occurrence
- Antibacterial activities and molecular identification of endophytic fungi isolated from mangrove Avicennia marina
- Sweet Basil (Ocimum basilicum L.): A Review of Its Botany, Phytochemistry, Pharmacological Activities, and Biotechnological Development
- Red Mangrove (Rhizophora stylosa Griff.): A Review of Its Botany, Phytochemistry, Pharmacological Activities, and Prospects
- Chemical constituents of Lasiodiplodia theobromae BPPCA 144, an endophytic fungus, isolated from Aglaia argentea Blume
- A Novel Limonoid from the Seeds of Chisocheton macrophyllus
- Arohynapene A Produced by Penicillium steckii JB-NW-2-1 Isolated from Avicennia marina and Its Cytotoxic Activities
- Steroids Produced by Cladosporium anthropophilum, an Endophytic Fungus, Isolated from Avicennia marina and Their Antibacterial Activity
- Comparative Studies of Two Indonesian Medicinal Plants, Bidara Upas and Adas: Antioxidant, Antidiabetic, and Antimicrobial Activities
- Cytotoxic Effect of Benzofuranoid Neolignans from Myristica fragrans Seeds Against Melanoma B16-F10 Cancer Cells
- One-pot Two-step Borylation/Fluorination Reaction of Dysobinin from Chisocheton macrophyllus and Its Cytotoxicity Against Cancer Cells
- Diterpenoid Compounds Derived from Meliaceae Plants and Their Biological Activities
- Lansioside E, an Onoceranoid-type Triterpenoid Isolated from the Fruit Peel of Lansium domesticum and Its Cytotoxic Activity Against MCF-7 Breast Cancer Cells
